Preferred Label : insulysin;
MeSH definition : An enzyme the catalyzes the degradation of insulin, glucagon and other polypeptides.
It is inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and
by thiol-blocking reagents such as N-ethylmaleimide, but not phosphoramidon. (Eur
J Biochem 1994;223:1-5) EC 3.4.24.56.;
MeSH synonym : Insulinase; enzyme, insulin-degrading; insulin protease; proteinase, insulin; insulin-degrading enzyme; insulin degrading enzyme; protease, insulin; insulin proteinase;
Registry Number MeSH : EC 3.4.24.56;
Wikipedia link : https://en.wikipedia.org/wiki/Insulin-degrading enzyme;
Is substance : O;
UNII : EC 3.4.24.56;
Origin ID : D007339;
UMLS CUI : C0021669;
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An enzyme the catalyzes the degradation of insulin, glucagon and other polypeptides.
It is inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and
by thiol-blocking reagents such as N-ethylmaleimide, but not phosphoramidon. (Eur
J Biochem 1994;223:1-5) EC 3.4.24.56.