" /> hypoglycins - CISMeF





Preferred Label : hypoglycins;

MeSH definition : Methylene cyclopropyl alanine and congeners isolated from the unripe edible fruit of the AKEE plant (BLIGHIA SAPIDA). Hypoglycin B is the gamma-glutamyl congener of hypoglycin A. They are very toxic and teratogenic, causing a syndrome called Jamaican vomiting sickness that includes a fall in blood glucose due to the interference of FATTY ACIDS and LEUCINE metabolism which leads to VOMITING, liver damage, CONVULSIONS and DEATH.;

MeSH annotation : Jamaican vomiting sickness : coordinate HYPOGLYCINS /pois (IM) with PLANT POISONING (IM);

Wikipedia link : https://en.wikipedia.org/wiki/Hypoglycins;

Is substance : O;

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Keyword's position in hierarchy(ies) : arborescence

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Methylene cyclopropyl alanine and congeners isolated from the unripe edible fruit of the AKEE plant (BLIGHIA SAPIDA). Hypoglycin B is the gamma-glutamyl congener of hypoglycin A. They are very toxic and teratogenic, causing a syndrome called Jamaican vomiting sickness that includes a fall in blood glucose due to the interference of FATTY ACIDS and LEUCINE metabolism which leads to VOMITING, liver damage, CONVULSIONS and DEATH.

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24/04/2025


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