bisbenzimidazole

Preferred Label : bisbenzimidazole;

MeSH definition : A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.;

MeSH synonym : pibenzimol;

CISMeF synonym : 33258, hoechst; p-(5-(5-(4-methylpiperazin-1-yl)benzimidazol-2-yl)benzimidazol-2-yl)phenol;

MeSH hyponym : bisbenzimide; NSC-322921; hoechst 33258; bisbenzimidazole trihydrochloride; NSC 322921; NSC322921; 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride; Hoe-33258; Hoe 33258; Hoe33258;

MeSH CAS label : 4-(5-(5-(4-Methylpiperazin-1-yl)benzimidazol-2- yl)benzimidazol-2-yl)phenol;

MeSH Related Number : bisbenzimidazole trihydrochloride; 23491-44-3 (Bisbenzimidazole); 23491-45-4;

Registry Number MeSH : 23491-44-3;

Related CAS MeSH : 23491-45-4 (Bisbenzimidazole trihydrochloride);

Codes EINECS : 245-689-0;

Is substance : O;

UNII : LHQ7J5KV9B;

InChIKey : INAAIJLSXJJHOZ-UHFFFAOYSA-N;

Details

Origin ID

D006690;

UMLS CUI

C0019832;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Bisbenzimide (substance) [SNOMED CT concept]
CISMeF manual mappings
- p-(5-(5-(4-methylpiperazin-1-yl)benzimidazol-2-yl)benzimidazol-2-yl)phenol [Substance BNPC]
Currated CISMeF NLP mapping
- Pibenzimol [NCIt concept]
Pharmacological action(s)
- filaricides [MeSH Descriptor]
- fluorescent dyes [MeSH Descriptor]
Record concept(s)
- NSC-322921 [MeSH concept]
- bisbenzimidazole [MeSH concept]
- bisbenzimidazole trihydrochloride [MeSH concept]
- hoechst 33258 [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-(2-(3-iodo-4-hydroxyphenyl)-6-benzimidazolyl)-6-(1-methyl-4-piperazyl)benzimidazole [MeSH Supplementary Concept]
- 2-(4-methoxyphenyl)-5-((4-methylpiperazin-1-yl)-3H-imidazo(4,5-b)pyridin-2-yl)-3H-imidazo(4,5-b)pyridine [MeSH Supplementary Concept]
- 4-(5-(5-(4-methyl-1-piperazinyl)-1H-imidazo(4,5-b)pyridin-2-yl)-2-benzoxazolyl)phenol [MeSH Supplementary Concept]
- H.A.-yellow [MeSH Supplementary Concept]
- V5851 [MeSH Supplementary Concept]
- compound E (Friedheim) [MeSH Supplementary Concept]
- hoe 43254 [MeSH Supplementary Concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pibenzimol [NCIt concept]
- p-(5-(5-(4-methylpiperazin-1-yl)benzimidazol-2-yl)benzimidazol-2-yl)phenol [Substance BNPC]

Keyword's position in hierarchy(ies) :

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