Preferred Label : hemicholinium 3;
MeSH definition : A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect
on the low affinity uptake system. Since choline is one of the components of ACETYLCHOLINE,
treatment with hemicholinium can deplete acetylcholine from cholinergic terminals.
Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.;
MeSH synonym : hemicholinium;
CISMeF synonym : 2,2'-(4,4'-biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium) dibromide;
MeSH CAS label : morpholinium, 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl)-, dibromide;
Registry Number MeSH : 312-45-8;
Codes EINECS : 206-227-3;
Is substance : O;
Origin ID : D006426;
UMLS CUI : C0018983;
Allowable qualifiers
- CISMeF manual mappings
- Pharmacological action(s)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
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- UMLS correspondences (same concept)
A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect
on the low affinity uptake system. Since choline is one of the components of ACETYLCHOLINE,
treatment with hemicholinium can deplete acetylcholine from cholinergic terminals.
Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.
