guanylyl imidodiphosphate

Preferred Label : guanylyl imidodiphosphate;

MeSH definition : A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2 . The nucleotide is a potent stimulator of ADENYLYL CYCLASES.;

MeSH synonym : gpp(nh)p; guanyl 5' imidodiphosphate; guanyl-5'-imidodiphosphate; imidodiphosphate, guanylyl; p(nh)ppg; guanosine 5'-(beta,gamma-imido)triphosphate; gmp-pnp; gmp-p(nh)p;

MeSH CAS label : 5'-Guanylic acid, monoanhydride with imidodiphosphoric acid;

Registry Number MeSH : 34273-04-6;

MeSH annotation : DF: GPPNHP;

Is substance : O;

Details

Origin ID

D006165;

UMLS CUI

C0018366;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- guanylyl imidodiphosphate [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-(2-nitro)phenylethyl-P(3)-guanylyl imidodiphosphate [MeSH Supplementary Concept]
- N(2)-(4-n-butylphenyl)-2'--deoxyguanosine 5'-imidotriphosphate [MeSH Supplementary Concept]
- chromium (III) bidentate guanosine 5'-(beta,gamma-imido)triphosphate [MeSH Supplementary Concept]
- technetium tc 99m 5'-guanylylimidodiphosphate [MeSH Supplementary Concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients