glycogen debranching enzyme system

Preferred Label : glycogen debranching enzyme system;

MeSH definition : 1,4-alpha-D-Glucan-1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase/dextrin 6 alpha-D-glucanohydrolase. An enzyme system having both 4-alpha-glucanotransferase (EC 2.4.1.25) and amylo-1,6-glucosidase (EC 3.2.1.33) activities. As a transferase it transfers a segment of a 1,4-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-D-glucan. As a glucosidase it catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. Amylo-1,6-glucosidase activity is deficient in glycogen storage disease type III.;

MeSH synonym : transfer glucosidase; transfer-glucosidase;

MeSH hyponym : glycogen debranching enzyme; Debranching Enzyme, Glycogen; Enzyme, Glycogen Debranching;

MeSH annotation : /defic: consider also GLYCOGEN STORAGE DISEASE TYPE III;

Wikipedia link : https://en.wikipedia.org/wiki/Glycogen debranching enzyme;

Is substance : O;

Details

Origin ID

D006004;

UMLS CUI

C0017915;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- Igd1 protein, S cerevisiae [MeSH Supplementary Concept]
Record concept(s)
- glycogen debranching enzyme [MeSH concept]
- glycogen debranching enzyme system [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4 alpha-glucanotransferase [MeSH Supplementary Concept]
- DPE2 protein, Arabidopsis [MeSH Supplementary Concept]
- GBE1 protein, human [MeSH Supplementary Concept]
- amylo-1,6-glucosidase [MeSH Supplementary Concept]
See also
- glycogen storage disease type iii [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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