glutathione synthase

Preferred Label : glutathione synthase;

MeSH definition : One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.3.;

MeSH synonym : synthase, glutathione; glutathione synthetase; synthetase, glutathione;

MeSH CAS label : gamma-L-Glutamyl-L-cysteine:glycine ligase (ADP-forming);

MeSH Related Number : 9023-62-5 (CAS RN);

Registry Number MeSH : EC 6.3.2.3;

Is substance : O;

UNII : EC 6.3.2.3;

Details

Origin ID

D005981;

UMLS CUI

C0017834;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Glutathione synthetase [OMIM gene]
- glutathione synthase activity [GO term]
- glutathione synthetase [HGNC gene]
- glutathione synthetase [ORDO Gene]
False automatic mappings
- Glutathione synthetase deficiency [ORDO Disease]
- Reduced glutathione synthetase level [HPO term]
Manual NTBT mappings (CISMeF)
- Hemolytic anemia due to hexose monophosphate shunt and glutathione metabolism anomalies [ORDO Disease]
- Rare constitutional hemolytic anemia [ORDO Disease]
Record concept(s)
- glutathione synthase [MeSH concept]
Related MeSH Supplementary Concept(s)
- GSH2 protein, Arabidopsis [MeSH Supplementary Concept]
- glutathione synthetase deficiency [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Glutathione synthetase deficiency [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Glutathione synthase [LOINC component]
- Glutathione synthase (substance) [SNOMED CT concept]
- glutathione synthase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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