MeSH definition : Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine
(globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate
in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens.
The accumulation of globoside in tissue, due to a defect in hexosaminidases A and
B, is the cause of Sandhoff disease.;
MeSH hyponym : cytolipins; Lacto-N-tetraosylceramide; Lacto N tetraosylceramide; Lactoneotetraosylceramide; Lacto-N-neotetraosylceramide; Lacto N neotetraosylceramide;
Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine
(globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate
in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens.
The accumulation of globoside in tissue, due to a defect in hexosaminidases A and
B, is the cause of Sandhoff disease.