multigene family

Preferred Label : multigene family;

MeSH definition : A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed);

MeSH synonym : families, multigene; family, multigene; multigene families;

MeSH hyponym : gene clusters; genes, reiterated; Gene, Reiterated; Reiterated Gene; Reiterated Genes; Cluster, Gene; Clusters, Gene; Gene Cluster;

Details

Origin ID

D005810;

UMLS CUI

C0017363;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- ethics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- GRAP Gene [NCIt concept]
- Gene cluster [EDAM data]
- Gene cluster [FMA entity]
- Reiterated gene (substance) [SNOMED CT concept]
- reiterated gene [SNOMED Notion]
Indexing information
- CRCT1 protein, human [MeSH Supplementary Concept]
- DNA B-26 [MeSH Supplementary Concept]
- KaiA protein, cyanobacteria [MeSH Supplementary Concept]
- KaiB protein, cyanobacteria [MeSH Supplementary Concept]
- KaiC protein, cyanobacteria [MeSH Supplementary Concept]
- TBX15 protein, mouse [MeSH Supplementary Concept]
- tbx15 protein, zebrafish [MeSH Supplementary Concept]
Record concept(s)
- gene clusters [MeSH concept]
- genes, reiterated [MeSH concept]
- multigene family [MeSH concept]
See also
- gene duplication [MeSH Descriptor]
- genes, duplicate [MeSH Descriptor]
- repetitive sequences, nucleic acid [MeSH Descriptor]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
Validated automatic mappings to NTBT
- Gene Family [NCIt concept]

Keyword's position in hierarchy(ies) :

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