free radicals - CISMeF

Preferred Label : free radicals;

MeSH definition : Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.; Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. Free radicals include reactive oxygen and nitrogen species (RONS). They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.;

MeSH synonym : Free Radical;

CISMeF synonym : radicals, free; Radical, Free;

Wikipedia automatic translation : Radical (chemistry);

MeSH annotation : IM GEN only; usually NIM with coord IM;

Wikipedia link : https://en.wikipedia.org/wiki/Radical (chemistry);

Is substance : O;

Details

Origin ID

D005609;

UMLS CUI

C0016693;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- free radical [Artificial nutrition thesaurus concept]
Indexing information
- (2,3,5,6-tetrachloro-4-nitrophenyl)methyl radical [MeSH Supplementary Concept]
- 1,1-diphenyl-2-picrylhydrazyl [MeSH Supplementary Concept]
- 1-chloro-2,2,2-trifluoroethyl radical [MeSH Supplementary Concept]
- 1-hydroxyethyl radical [MeSH Supplementary Concept]
- 1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl 1-adamantylacetate [MeSH Supplementary Concept]
- 2,6-di-(t)butyl-4-(4'-nitrophenyl)phenoxyl radical [MeSH Supplementary Concept]
- 2,6-dimethoxysemiquinone radicals [MeSH Supplementary Concept]
- 4,4'-azobis(4-cyanovaleric acid) [MeSH Supplementary Concept]
- 4,4'-di-(tert-butyl)diphenyl-1-nitroxy [MeSH Supplementary Concept]
- 4-(nitrophenyl)phenoxyl radical [MeSH Supplementary Concept]
- 5-yl-6-hydroxycytosine [MeSH Supplementary Concept]
- N-hydroxy-4-(4-chlorophenyl)thiazole-2(3H)-thione [MeSH Supplementary Concept]
- N-succinyl-4-amino-2,2,6,6-tetramethylpiperidine-1-oxyl [MeSH Supplementary Concept]
- alkoxyl radical [MeSH Supplementary Concept]
- bis(3,5-dimethyl-5-hydroxymethyl-2-oxomorpholin-3-yl) [MeSH Supplementary Concept]
- carboxyl radical [MeSH Supplementary Concept]
- cumene hydroperoxide [MeSH Supplementary Concept]
- free radical reductase [MeSH Supplementary Concept]
- hydroxanthommatin [MeSH Supplementary Concept]
- methyl radical [MeSH Supplementary Concept]
- nitroxyl [MeSH Supplementary Concept]
- perhydroxyl radical [MeSH Supplementary Concept]
- phenoxy radical [MeSH Supplementary Concept]
- semidehydroascorbic acid [MeSH Supplementary Concept]
- sulfate radical [MeSH Supplementary Concept]
- tert-butoxy [MeSH Supplementary Concept]
- tyrosyl radical Y(D) [MeSH Supplementary Concept]
- tyrosyl radical YZ [MeSH Supplementary Concept]
Record concept(s)
- free radicals [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,5-diisopropyl-6-oxo-verdazyl [MeSH Supplementary Concept]
- 2'-deoxy-5-methyleneuridin-5-yl [MeSH Supplementary Concept]
- 4-Oxidobenzyl Radical [MeSH Supplementary Concept]
- HOOO radical [MeSH Supplementary Concept]
- thioformyl [MeSH Supplementary Concept]
- tocopheroxy radical [MeSH Supplementary Concept]
- tyrosine radical [MeSH Supplementary Concept]
- verdazyl radical [MeSH Supplementary Concept]
See also
- free radical scavengers [MeSH Descriptor]
- reactive oxygen species [MeSH Descriptor]
- spin trapping [MeSH Descriptor]
Semantic type(s)
- Inorganic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Free Radical [NCIt concept]
- Free radical (substance) [SNOMED CT concept]
- free radical [IUPAC Term]
- free radical [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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