formate-tetrahydrofolate ligase

Preferred Label : formate-tetrahydrofolate ligase;

MeSH definition : A carbon-nitrogen ligase that catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate in the presence of ATP. In higher eukaryotes the enzyme also contains METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP ) and METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE activity.;

MeSH synonym : ligase, formate-tetrahydrofolate; synthetase, formyltetrahydrofolate; formylase, tetrahydrofolate; formyltetrahydrofolate synthetase; tetrahydrofolate formylase; formate tetrahydrofolate ligase;

MeSH CAS label : formate:tetrahydrofolate ligase (ADP-forming);

MeSH Related Number : 9023-66-9 (CAS RN);

Registry Number MeSH : EC 6.3.4.3;

Wikipedia link : https://en.wikipedia.org/wiki/Formate-tetrahydrofolate ligase;

Is substance : O;

UNII : EC 6.3.4.3;

Details

Origin ID

D005574;

UMLS CUI

C0016597;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Formate-tetrahydrofolate ligase (substance) [SNOMED CT concept]
- formate-tetrahydrofolate ligase [SNOMED Notion]
Record concept(s)
- Formate-Tetrahydrofolate ligase [MeSH concept]
Related MeSH Supplementary Concept(s)
- Mthfd1 protein, mouse [MeSH Supplementary Concept]
- formyl-methenyl-methylenetetrahydrofolate synthetase [MeSH Supplementary Concept]
See also
- methenyltetrahydrofolate cyclohydrolase [MeSH Descriptor]
- methylenetetrahydrofolate dehydrogenase (NADP) [MeSH Descriptor]
See also inter- (CISMeF)
- formate-tetrahydrofolate ligase activity [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Formate-tetrahydrofolate ligase (substance) [SNOMED CT concept]
- formate-tetrahydrofolate ligase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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