floxuridine - CISMeF

Preferred Label : floxuridine;

MeSH definition : An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.;

MeSH synonym : 5-fluorodeoxyuridine; 5 fluorodeoxyuridine; fluorodeoxyuridine; 5-fudr; fudr;

MeSH CAS label : uridine, 2'-deoxy-5-fluoro-;

MeSH Related Number : 50-91-9 (Floxuridine);

Registry Number MeSH : 50-91-9;

MeSH annotation : an antiviral & antineoplastic antimetabolite;

Wikipedia link : https://en.wikipedia.org/wiki/5-fluorodeoxyuridine;

Codes EINECS : 200-072-5;

Is substance : O;

UNII : 039LU44I5M;

InChIKey : ODKNJVUHOIMIIZ-RRKCRQDMSA-N;

Details

Origin ID

D005467;

UMLS CUI

C0016343;

ATC code(s)
- floxuridine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Floxuridine [ICHI extension code]
- doxifluridine [Substance BNPC]
- methyl 2-[[2-methyl-3-[4-(1-methylethyl)phenyl]propylidene]amino]benzoate [Substance BNPC]
CISMeF manual mappings
- floxuridine [Substance BNPC]
Currated CISMeF NLP mapping
- Floxuridine [ICD-11 Extension code]
- Floxuridine [NCIt concept]
- Floxuridine (substance) [SNOMED CT concept]
- floxuridine [SNOMED Notion]
Pharmacological action(s)
- antimetabolites, antineoplastic [MeSH Descriptor]
Record concept(s)
- floxuridine [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-(2'-deoxy-2'-fluororibofuranosyl)-5-dodecynyluracil [MeSH Supplementary Concept]
- 1-(2'-deoxy-2'-fluororibofuranosyl)-5-tetradecynyluracil [MeSH Supplementary Concept]
- 1-(2-deoxy-2-fluoro-3-O-(1-methyl-1,4-dihydropyridyl-3-carbonyl)ribofuranosyl)-5-(2-iodovinyl)uracil [MeSH Supplementary Concept]
- 2',2'-difluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- 2'-amino-2'-deoxy-5-fluorouridine [MeSH Supplementary Concept]
- 2'-deoxy-2',4'-difluorouridine [MeSH Supplementary Concept]
- 2'-deoxy-3',5'-di-O-acetyl-5-fluoro-3-(3-methylbenzoyl)uridine [MeSH Supplementary Concept]
- 2'-deoxy-5-fluorouridylyl-(3'-5')-2'-deoxy-5-fluoro-N(4)-octadecylcytidine [MeSH Supplementary Concept]
- 2'fluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- 3'-O-crotonylfloxuridine [MeSH Supplementary Concept]
- 3'-O-propargyl-5-fluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- 3'-azido-2',3'-dideoxy-5-fluorouridine phosphoramidate [MeSH Supplementary Concept]
- 3'-octanoyl-5-fluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- 5'-(2-(2-Nitrophenyl)-2-methylpropionyl)-2'-deoxy-5-fluorouridine [MeSH Supplementary Concept]
- 5'-O-palmitoyl-5-fluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- 5'-isoleucyl-glycyl-floxuridine [MeSH Supplementary Concept]
- 5'-octanoyl-5-fluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- 5'-phenylalanyl-glycyl-floxuridine [MeSH Supplementary Concept]
- 5'-phenylalanyl-tyrosyl-floxuridine [MeSH Supplementary Concept]
- 5'deoxy-4',5-difluorouridine [MeSH Supplementary Concept]
- 5-(2-fluoroethyl)-2'-deoxyuridine [MeSH Supplementary Concept]
- 5-(2-iodovinyl)-1-(2'-fluoro-2'-deoxyuridine) [MeSH Supplementary Concept]
- 5-bromo-1-(2-fluoro-2-deoxyribofuranosyl)uracil [MeSH Supplementary Concept]
- 5-chloro-1-(2'-fluoro-2'-deoxyribofuranosyl)uracil [MeSH Supplementary Concept]
- 5-fluoro-1-(2'-deoxy-2'-fluoro-ribofuranosyl)uracil [MeSH Supplementary Concept]
- 5-fluoro-1-(2'-fluoro-2'-deoxyribofuranosyl)uracil [MeSH Supplementary Concept]
- 5-fluoro-2'-deoxyuridylyl-(3'-5')-arabinocytidine [MeSH Supplementary Concept]
- 5-fluoro-5'-O-nitro-2'-deoxyuridine [MeSH Supplementary Concept]
- 5-fluorodeoxyuridine-dipalmitate [MeSH Supplementary Concept]
- 5-iodo-1-(2-fluoro-2-deoxyribofuranosyl)uracil [MeSH Supplementary Concept]
- BOF A1 [MeSH Supplementary Concept]
- DAC protocol 2 [MeSH Supplementary Concept]
- FF 707 [MeSH Supplementary Concept]
- FLAP protocol [MeSH Supplementary Concept]
- FMB protocol [MeSH Supplementary Concept]
- FUDRAM protocol [MeSH Supplementary Concept]
- MAC-VD protocol [MeSH Supplementary Concept]
- N(3)-methyl-5'-deoxy-5-fluorouridine [MeSH Supplementary Concept]
- N(4)-palmitoyl-2'-deoxycytidylyl-(3'-5')-5-fluoro-2'-deoxyuridine [MeSH Supplementary Concept]
- NUC-3073 [MeSH Supplementary Concept]
- TK 117 [MeSH Supplementary Concept]
- doxifluridine [MeSH Supplementary Concept]
- fluorodeoxyuridine triphosphate [MeSH Supplementary Concept]
- thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing floxuridine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Floxuridine [ICD-11 Extension code]
- Floxuridine [NCIt concept]
- Floxuridine (substance) [SNOMED CT concept]
- Product containing floxuridine (medicinal product) [SNOMED CT concept]
- floxuridine [Substance BNPC]
- floxuridine [SNOMED Notion]
- floxuridine [ATC Code]
Validated automatic mappings to BTNT
- floxuridine [ATC Code]

Keyword's position in hierarchy(ies) :

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