flunarizine - CISMeF

Preferred Label : flunarizine;

MeSH definition : Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.;

MeSH synonym : flunarizin;

CISMeF synonym : 30484-77-6 (Flunarizine hydrochloride);

MeSH hyponym : R-14950; sibelium; Flunarizine Hydrochloride; Hydrochloride, Flunarizine; Flunarizine Dihydrochloride; Dihydrochloride, Flunarizine; R 14950; R14950;

MeSH CAS label : piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)-, (E)-;

MeSH Related Number : flunarizine hydrochloride; 30484-77-6 (di-HCl); 52468-60-7 (Flunarizine); C11102TO53;

Registry Number MeSH : 52468-60-7;

Related CAS MeSH : C11102TO53 (Flunarizine hydrochloride);

Wikipedia link : https://en.wikipedia.org/wiki/Flunarizine;

Codes EINECS : 257-937-5;

Is substance : O;

UNII : R7PLA2DM0J;

InChIKey : SMANXXCATUTDDT-QPJJXVBHSA-N;

Details

Origin ID

D005444;

UMLS CUI

C0016295;

ATC code(s)
- flunarizine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- (e)-1-[bis(4-fluorophenyl)methyl]-4-cinnamylpiperazine dihydrochloride [Substance BNPC]
Currated CISMeF NLP mapping
- Flunarizine [ICD-11 Extension code]
- Flunarizine [ICHI extension code]
- Flunarizine [SMS substance]
- Flunarizine [NCIt concept]
- Flunarizine (substance) [SNOMED CT concept]
Pharmacological action(s)
- anticonvulsants [MeSH Descriptor]
- calcium channel blockers [MeSH Descriptor]
- histamine h1 antagonists [MeSH Descriptor]
- neurotransmitter agents [MeSH Descriptor]
- vasodilator agents [MeSH Descriptor]
Record concept(s)
- Flunarizine Hydrochloride [MeSH concept]
- R-14950 [MeSH concept]
- flunarizine [MeSH concept]
- sibelium [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-(bis(4-fluorophenyl)methyl)-4-(3-(4'-hydroxyphenyl)-2-propenyl)piperazine [MeSH Supplementary Concept]
- GBR 13069 [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- histamine h1 antagonists [MeSH Descriptor]
See also inter- (CISMeF)
- (e)-1-[bis(4-fluorophenyl)methyl]-4-cinnamylpiperazine dihydrochloride [Substance BNPC]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Flunarizine [ICD-11 Extension code]
- Flunarizine [NCIt concept]
- Flunarizine (substance) [SNOMED CT concept]
- Product containing flunarizine (medicinal product) [SNOMED CT concept]
- flunarizine [ATC Code]
- flunarizine [Substance BNPC]

Keyword's position in hierarchy(ies) :

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