fibrinolysin - CISMeF

Preferred Label : fibrinolysin;

MeSH definition : A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.;

MeSH synonym : protease f; Plasmin; glu-plasmin; glu plasmin;

CISMeF synonym : aventis pharma brand of plasmin;

MeSH hyponym : fibrogammin; thrombolysin;

Registry Number MeSH : EC 3.4.21.7;

Wikipedia link : https://en.wikipedia.org/wiki/Plasmin;

Is substance : O;

UNII : EC 3.4.21.7;

Details

Origin ID

D005341;

UMLS CUI

C0016016;

ATC code(s)
- fibrinolysin [ATC Code]
- fibrinolysin and desoxyribonuclease [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Endopeptidase (substance) [SNOMED CT concept]
- Fibrogammin® [Blood Transfusion thesaurus concept]
- Peptidase [NCIt concept]
- Plasminogen [NCIt concept]
- Thrombolysin [ICD-11 Extension code]
- Thrombolysin [ICHI extension code]
- obsolete plasmin activity [GO term]
- plasmin [EMDN type]
- proteases [IUPAC Term]
Currated CISMeF NLP mapping
- Fibrinolysin [NCIt concept]
- Fibrinolysin [ICD-11 Extension code]
- Fibrinolysin [SMS substance]
- Fibrinolysin (substance) [SNOMED CT concept]
- Plasmin (substance) [SNOMED CT concept]
- plasmin [SNOMED Notion]
- plasmin [Substance BNPC]
- plasmin [Blood Transfusion thesaurus concept]
- plasmin [medical devices type]
Indexing information
- 4-(beta-amidinoethenyl)phenyl-4-guanidinobenzoate dimethanesulfonate [MeSH Supplementary Concept]
- 4-amidino-2-benzoylphenyl 4-guanidinobenzoate dimethanesulfonate [MeSH Supplementary Concept]
- N,N-dimethylamino-4-(4'-guanidinobenzoyloxy)benzylcarbonyloxyglycolate [MeSH Supplementary Concept]
- alanyl-phenylalanyl-lysine fluoromethane [MeSH Supplementary Concept]
- bdellastasin [MeSH Supplementary Concept]
- cassigarol A [MeSH Supplementary Concept]
- lysyl-methionyl(sulfone)-tyrosyl-arginine [MeSH Supplementary Concept]
- nafamostat [MeSH Supplementary Concept]
- plasmin receptor [MeSH Supplementary Concept]
- plasminase A [MeSH Supplementary Concept]
- plasminase B [MeSH Supplementary Concept]
- textilinin [MeSH Supplementary Concept]
Pharmacological action(s)
- fibrinolytic agents [MeSH Descriptor]
Record concept(s)
- fibrinolysin [MeSH concept]
- fibrogammin [MeSH concept]
- thrombolysin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4-anisoyl activator-free plasmin [MeSH Supplementary Concept]
- CY 218 [MeSH Supplementary Concept]
- carbamyl plasmin A [MeSH Supplementary Concept]
- deoxyribonuclease, plasmin drug combination [MeSH Supplementary Concept]
- gussurobin [MeSH Supplementary Concept]
- lys-plasmin [MeSH Supplementary Concept]
- microplasmin [MeSH Supplementary Concept]
- miniplasmin [MeSH Supplementary Concept]
- plasmin heavy chain-urokinase conjugate [MeSH Supplementary Concept]
- plasmin-alpha(2)-macroglobulin complex [MeSH Supplementary Concept]
- plasmin-plasmin inhibitor complex [MeSH Supplementary Concept]
- streptokinase-B-chain plasmin complex [MeSH Supplementary Concept]
- technetium tc 99m plasmin [MeSH Supplementary Concept]
- uroplasmin [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing plasmin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fibrinolysin [NCIt concept]
- Fibrinolysin (substance) [SNOMED CT concept]
- Product containing plasmin (medicinal product) [SNOMED CT concept]
- fibrinolysin [ATC Code]
- plasmin [SNOMED Notion]
Validated automatic mappings to BTNT
- fibrinolysin [ATC Code]

Keyword's position in hierarchy(ies) :

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