Preferred Label : DNA polymerase III;
MeSH definition : A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms
but may be present in higher organisms. Use also for a more complex form of DNA polymerase
III designated as DNA polymerase III* or pol III* which is 15 times more active biologically
than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and
5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same
template-primer dependence as pol II. EC 2.7.7.7.; A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms
but may be present in higher organisms. Use also for a more complex form of DNA polymerase
III designated as DNA polymerase III* or pol III* which is 15 times more active biologically
than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and
5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same
template-primer dependence as pol II.;
MeSH synonym : dna dependent dna polymerase iii; dna polymerase delta; dna-dependent dna polymerase iii; polymerase delta, dna; polymerase iii, dna; DNA pol III;
CISMeF synonym : pol iii;
Registry Number MeSH : EC 2.7.7.-;
Is substance : O;
UNII : EC 2.7.7.7;
Origin ID : D004258;
UMLS CUI : C0012890;
Allowable qualifiers
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- Currated CISMeF NLP mapping
- Indexing information
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- UMLS correspondences (same concept)
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms
but may be present in higher organisms. Use also for a more complex form of DNA polymerase
III designated as DNA polymerase III* or pol III* which is 15 times more active biologically
than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and
5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same
template-primer dependence as pol II. EC 2.7.7.7.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms
but may be present in higher organisms. Use also for a more complex form of DNA polymerase
III designated as DNA polymerase III* or pol III* which is 15 times more active biologically
than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and
5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same
template-primer dependence as pol II.
