Preferred Label : DNA polymerase II;
MeSH definition : A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms.
It may be present in higher organisms and has an intrinsic molecular activity only
5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is
effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides
as template, and is inhibited by sulfhydryl reagents. EC 2.7.7.7.; A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms.
It may be present in higher organisms and has an intrinsic molecular activity only
5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is
effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides
as template, and is inhibited by sulfhydryl reagents.;
MeSH synonym : dna dependent dna polymerase ii; dna polymerase epsilon; dna-dependent dna polymerase ii; DNA pol II;
CISMeF synonym : pol ii; polymerase epsilon, dna; polymerase ii, dna;
Registry Number MeSH : EC 2.7.7.-;
Is substance : O;
UNII : EC 2.7.7.7;
Origin ID : D004257;
UMLS CUI : C0012889;
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A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms.
It may be present in higher organisms and has an intrinsic molecular activity only
5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is
effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides
as template, and is inhibited by sulfhydryl reagents. EC 2.7.7.7.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms.
It may be present in higher organisms and has an intrinsic molecular activity only
5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is
effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides
as template, and is inhibited by sulfhydryl reagents.
