diazooxonorleucine

Preferred Label : diazooxonorleucine;

MeSH definition : An amino acid that inhibits phosphate-activated glutaminase and interferes with glutamine metabolism. It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil. (From Merck Index, 11th ed);

MeSH synonym : 6 diazo 5 oxo l norleucine; 6-diazo-5-oxo-l-norleucine;

MeSH CAS label : norleucine, 6-diazo-5-oxo-;

MeSH Related Number : 764-17-0 (Diazooxonorleucine);

Registry Number MeSH : 764-17-0;

Is substance : O;

UNII : 03J0H273KZ;

InChIKey : YCWQAMGASJSUIP-YFKPBYRVSA-N;

Details

Origin ID

D003980;

UMLS CUI

C0012020;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Diazooxonorleucine [NCIt concept]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
- antimetabolites, antineoplastic [MeSH Descriptor]
Record concept(s)
- diazooxonorleucine [MeSH concept]
Related MeSH Supplementary Concept(s)
- 6-diazo-5-oxo-L-norleucylglycine [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Diazooxonorleucine [NCIt concept]

Keyword's position in hierarchy(ies) :

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