complement C3b

Preferred Label : complement C3b;

MeSH definition : The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g.;

MeSH synonym : component 3b, complement; complement 3b; c3b, complement; complement component 3b; c3b complement; complement, C3b;

MeSH hyponym : inactivated C3b; C3b, Inactivated; iC3b; C3bi;

MeSH CAS label : complement C3b;

Registry Number MeSH : 80295-43-8;

MeSH annotation : /antag: consider COMPLEMENT C3B INACTIVATOR PROTEINS;

Is substance : O;

Details

Origin ID

D003179;

UMLS CUI

C0009511;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Complement C3 Beta Chain [NCIt concept]
- Complement C3b Measurement [NCIt concept]
- Complement factor I [SNOMED Notion]
- Complement factor I [LOINC component]
- Complement factor I [OMIM gene]
Currated CISMeF NLP mapping
- Complement C3b [LOINC component]
- Complement component C3b (substance) [SNOMED CT concept]
- complement component c3b [SNOMED Notion]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- complement C3b [MeSH concept]
- inactivated C3b [MeSH concept]
Related MeSH Supplementary Concept(s)
- C3 beta c [MeSH Supplementary Concept]
- complement C3bBa complex [MeSH Supplementary Concept]
- complement C3d,g [MeSH Supplementary Concept]
- complement C3d-k [MeSH Supplementary Concept]
- complement C3e [MeSH Supplementary Concept]
- complement C3f [MeSH Supplementary Concept]
- complement C3f-des-arginine [MeSH Supplementary Concept]
- complement C3g [MeSH Supplementary Concept]
See also
- receptors, complement 3b [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Active C3b (substance) [SNOMED CT concept]
- Complement C3b [LOINC component]
- Complement component C3b (substance) [SNOMED CT concept]
- active c3b [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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