colorectal neoplasms, hereditary nonpolyposis

Preferred Label : colorectal neoplasms, hereditary nonpolyposis;

MeSH definition : A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.;

MeSH synonym : hereditary nonpolyposis colorectal neoplasms; familial nonpolyposis colon cancer;

CISMeF acronym : HNPCC;

MeSH hyponym : hereditary nonpolyposis colorectal cancer; Colorectal Cancer Hereditary Nonpolyposis; Lynch Syndrome I; Lynch Cancer Family Syndrome I; Lynch Syndrome; Syndrome, Lynch; Colon Cancer, Familial Nonpolyposis; Hereditary Nonpolyposis Colon Cancer; Colon Cancer, Familial Nonpolyposis, Type 1; Familial Nonpolyposis Colon Cancer Type 1; Colorectal Cancer, Hereditary Nonpolyposis, Type 1; Hereditary Nonpolyposis Colorectal Cancer Type 1;

MeSH annotation : DF: HNPCC;

Wikipedia link : https://en.wikipedia.org/wiki/Familial nonpolyposis colon cancer;

Details

Origin ID

D003123;

UMLS CUI

C0009405;

Allowable qualifiers
- blood [MeSH Qualifier]
- blood supply [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemically induced [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- complications [MeSH Qualifier]
- diagnosis [MeSH Qualifier]
- diagnostic imaging [MeSH Qualifier]
- diet therapy [MeSH Qualifier]
- drug therapy [MeSH Qualifier]
- economics [MeSH Qualifier]
- embryology [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- epidemiology [MeSH Qualifier]
- ethnology [MeSH Qualifier]
- etiology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- mortality [MeSH Qualifier]
- nursing [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiopathology [MeSH Qualifier]
- prevention and control [MeSH Qualifier]
- psychology [MeSH Qualifier]
- radiotherapy [MeSH Qualifier]
- rehabilitation [MeSH Qualifier]
- secondary [MeSH Qualifier]
- surgery [MeSH Qualifier]
- therapy [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
- veterinary [MeSH Qualifier]
- virology [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Lynch 1 Syndrome [NCIt concept]
- Lynch syndrome 1 [DO Concept]
- hnpcc [medical devices type]
- mutL homolog 1 [ORDO Gene]
- mutS homolog 2 [ORDO Gene]
Currated CISMeF NLP mapping
- Lynch Syndrome [NCIt concept]
- hereditary nonpolyposis colorectal neoplasm [Disease (Nov.)]
- lynch syndrome I (site-specific colonic cancer) [MeSH Supplementary Concept]
DO Cross reference
- Lynch syndrome [DO Concept]
ORDO relation(s)
- Lynch syndrome [ORDO Disease]
Record concept(s)
- Lynch Syndrome [MeSH concept]
- Lynch Syndrome I [MeSH concept]
- colorectal neoplasms, hereditary nonpolyposis [MeSH concept]
- hereditary nonpolyposis colorectal cancer [MeSH concept]
Related MeSH Supplementary Concept(s)
- colorectal cancer, hereditary nonpolyposis, type 3 [MeSH Supplementary Concept]
- colorectal cancer, hereditary nonpolyposis, type 4 [MeSH Supplementary Concept]
- colorectal cancer, hereditary nonpolyposis, type 5 [MeSH Supplementary Concept]
- colorectal cancer, hereditary nonpolyposis, type 6 [MeSH Supplementary Concept]
- colorectal cancer, hereditary nonpolyposis, type 7 [MeSH Supplementary Concept]
- colorectal cancer, hereditary nonpolyposis, type 8 [MeSH Supplementary Concept]
- lynch syndrome I (site-specific colonic cancer) [MeSH Supplementary Concept]
See also inter- (CISMeF)
- DNA Mismatch Repair Protein Mlh1 [NCIt concept]
- Familial ovarian cancer [ORDO Disease]
- MSH2 wt Allele [NCIt concept]
- Non-polyposis Turcot syndrome [ORDO Disease]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
Validated automatic mappings to NTBT
- Inherited cancer-predisposing syndrome [ORDO Disease]

Keyword's position in hierarchy(ies) :

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