MeSH definition : A condition produced by a deficiency of CHOLINE in animals. Choline is known as a
lipotropic agent because it has been shown to promote the transport of excess fat
from the liver under certain conditions in laboratory animals. Combined deficiency
of choline (included in the B vitamin complex) and all other methyl group donors causes
liver cirrhosis in some animals. Unlike compounds normally considered as vitamins,
choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary
& Encyclopedia of Laboratory Medicine and Technology, 1984);
A condition produced by a deficiency of CHOLINE in animals. Choline is known as a
lipotropic agent because it has been shown to promote the transport of excess fat
from the liver under certain conditions in laboratory animals. Combined deficiency
of choline (included in the B vitamin complex) and all other methyl group donors causes
liver cirrhosis in some animals. Unlike compounds normally considered as vitamins,
choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary
& Encyclopedia of Laboratory Medicine and Technology, 1984)