Cerebroside-Sulfatase

Preferred Label : Cerebroside-Sulfatase;

MeSH definition : An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.;

MeSH synonym : sulfatidate sulfatase; arylsulfatase a; sulfatase, sulfatidate; cerebroside sulfatase;

MeSH CAS label : Cerebroside-3-sulfate 3-sulfohydrolase;

Registry Number MeSH : EC 3.1.6.8;

MeSH annotation : /defic: consider also LEUKODYSTROPHY, METACHROMATIC;

Wikipedia link : https://en.wikipedia.org/wiki/Cerebroside-3-sulfate 3-sulfohydrolase;

Is substance : O;

UNII : EC 3.1.6.8;

Details

Origin ID

D002553;

UMLS CUI

C0007804;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Cerebroside-Sulfatase [MeSH concept]
Related MeSH Supplementary Concept(s)
- galactocerebroside sulfate sulfatidase [MeSH Supplementary Concept]
See also
- leukodystrophy, metachromatic [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cerebroside sulfatase [LOINC component]
- Cerebroside-sulfatase (substance) [SNOMED CT concept]
- cerebroside-sulfatase [SNOMED Notion]
Validated automatic mappings to NTBT
- Arylsulfatase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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