cathepsins - CISMeF

Preferred Label : cathepsins;

MeSH definition : A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES.;

MeSH synonym : cathepsin;

Registry Number MeSH : EC 3.4.-;

MeSH annotation : note specifics;

Is substance : O;

Details

Origin ID

D002403;

UMLS CUI

C0007428;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Carboxypeptidase C (substance) [SNOMED CT concept]
- Cathepsin (substance) [SNOMED CT concept]
- Cathepsin A [LOINC component]
- Cathepsin a [OMIM gene]
- Lysosomal carboxypeptidase B (substance) [SNOMED CT concept]
- cathepsin A [ORDO Gene]
- cathepsin A [HGNC gene]
- cathepsin b [SNOMED Notion]
- cathepsin d [SNOMED Notion]
- cathepsin g [SNOMED Notion]
- cathepsin h [SNOMED Notion]
- cathepsin l [SNOMED Notion]
- cathepsin r [SNOMED Notion]
Currated CISMeF NLP mapping
- Cathepsin [NCIt concept]
Indexing information
- 5-(2-morpholin-4-ylethoxy)benzofuran-2-carboxylic acid (3-methyl-1-(3-oxo-1-(2-(3-pyridin-2-ylphenyl)acetyl)azepan-4-ylcarbamoyl)butyl)amide [MeSH Supplementary Concept]
- E 64 [MeSH Supplementary Concept]
- N-(benzyloxycarbonyl)-phenylalanyl-tyrosinal [MeSH Supplementary Concept]
- WF 14861 [MeSH Supplementary Concept]
- diaminopyrrolidinone [MeSH Supplementary Concept]
- leupeptin [MeSH Supplementary Concept]
Record concept(s)
- cathepsins [MeSH concept]
Related MeSH Supplementary Concept(s)
- AhCP1 enzyme [MeSH Supplementary Concept]
- CTSO protein, human [MeSH Supplementary Concept]
- CTSV protein, human [MeSH Supplementary Concept]
- CsCF-6 protein, clonorchis sinensis [MeSH Supplementary Concept]
- Cts7 protein, mouse [MeSH Supplementary Concept]
- Cts8 protein, mouse [MeSH Supplementary Concept]
- artemia cathepsin L-like protease [MeSH Supplementary Concept]
- cat-L1B protein, fasciola gigantica [MeSH Supplementary Concept]
- cathepsin J [MeSH Supplementary Concept]
- cathepsin L1, fasciola hepatica [MeSH Supplementary Concept]
- cathepsin L5 [MeSH Supplementary Concept]
- cathepsin M [MeSH Supplementary Concept]
- cathepsin N [MeSH Supplementary Concept]
- cathepsin Q [MeSH Supplementary Concept]
- cathepsin S [MeSH Supplementary Concept]
- cathepsin T [MeSH Supplementary Concept]
- cathepsin X, mouse [MeSH Supplementary Concept]
- cathepsin Y [MeSH Supplementary Concept]
- cathepsin-6 [MeSH Supplementary Concept]
- ctsla protein, zebrafish [MeSH Supplementary Concept]
- ctso protein, mouse [MeSH Supplementary Concept]
- phytepsin [MeSH Supplementary Concept]
- preprocathepsin B [MeSH Supplementary Concept]
- preprocathepsin C [MeSH Supplementary Concept]
- preprocathepsin H [MeSH Supplementary Concept]
- preprocathepsin L [MeSH Supplementary Concept]
- procathepsin K, Ser(139)-Ala(163)- [MeSH Supplementary Concept]
- procathepsin X, human [MeSH Supplementary Concept]
- silicatein alpha [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cathepsin [NCIt concept]
- Cathepsin (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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