Preferred Label : cathepsin b;
MeSH definition : A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The
enzyme is present in a variety of tissues and is important in many physiological and
pathological processes. In pathology, cathepsin B has been found to be involved in
DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.;
MeSH synonym : cathepsin b1;
CISMeF synonym : b, cathepsin; b-like proteinase, cathepsin; cathepsin b-like activity; activity, cathepsin b-like; b-like activity, cathepsin; b1, cathepsin; cathepsin b like activity;
Related MeSH term : cathepsin B-Like proteinase; Cathepsin B Like Proteinase; Proteinase, Cathepsin B-Like;
Registry Number MeSH : EC 3.4.22.1;
Wikipedia link : https://en.wikipedia.org/wiki/Cathepsin b;
Is substance : O;
UNII : EC 3.4.22.1;
Origin ID : D002401;
UMLS CUI : C0699919;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Indexing information
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The
enzyme is present in a variety of tissues and is important in many physiological and
pathological processes. In pathology, cathepsin B has been found to be involved in
DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.
