bromodeoxyuridine

Preferred Label : bromodeoxyuridine;

MeSH definition : A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.;

MeSH synonym : 5-bromo-2'-deoxyuridine; bromouracil deoxyriboside; brdu; 5-bromodeoxyuridine; Broxuridine; deoxyriboside, bromouracil; 5 bromo 2' deoxyuridine; budr; 5 bromodeoxyuridine;

MeSH hyponym : NSC-38297;

MeSH CAS label : uridine, 5-bromo-2'-deoxy-;

MeSH Related Number : 59-14-3 (Bromodeoxyuridine);

Registry Number MeSH : 59-14-3;

Wikipedia link : https://en.wikipedia.org/wiki/5-bromo-2'-deoxyuridine;

Codes EINECS : 200-415-9;

Is substance : O;

UNII : G34N38R2N1;

InChIKey : WOVKYSAHUYNSMH-RRKCRQDMSA-N;

Details

Origin ID

D001973;

UMLS CUI

C0006233;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- bromodeoxyuridine [Substance BNPC]
Currated CISMeF NLP mapping
- Broxuridine [ICD-11 Extension code]
- Broxuridine [NCIt concept]
Pharmacological action(s)
- antimetabolites, antineoplastic [MeSH Descriptor]
- antiviral agents [MeSH Descriptor]
- radiation-sensitizing agents [MeSH Descriptor]
Record concept(s)
- NSC-38297 [MeSH concept]
- bromodeoxyuridine [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-(3-hydroxy-4-(hydroxymethyl)-cyclopentyl)-5-(2-bromovinyl)-2,4-(1H,3H)-pyrimidinedione [MeSH Supplementary Concept]
- 2'-bromo-2'-deoxyuridine [MeSH Supplementary Concept]
- 3',5'-di-O-(4-chlorobenzoyl)-5-(2-dibromovinyl)-2'-deoxyuridine [MeSH Supplementary Concept]
- 3',5'-di-O-acetyl-5-(2-bromovinyl)-2'-deoxyuridine [MeSH Supplementary Concept]
- 3',5'-dioctanoyl-5-bromodeoxyuridine [MeSH Supplementary Concept]
- 5-(2-bromoethyl)-2'-deoxyuridine [MeSH Supplementary Concept]
- 5-(2-bromovinyl)-2'-deoxy-4'-thiouridine [MeSH Supplementary Concept]
- 5-(2-bromovinyl)-3-amino-2',3'-dideoxyuridine [MeSH Supplementary Concept]
- 5-bromo-2'-chloro-2'-deoxyuridine [MeSH Supplementary Concept]
- 5-bromo-5-ethyl-6-ethoxy-5,6-dihydro-2'-deoxyuridine [MeSH Supplementary Concept]
- 5-bromo-5-ethyl-6-ethoxy-5,6-dihydro-5'-O-valeryl-2'-deoxyuridine [MeSH Supplementary Concept]
- NB1011 [MeSH Supplementary Concept]
- ammonium 5-bromodeoxyuridine 5'-methylphosphonate [MeSH Supplementary Concept]
- brivudine [MeSH Supplementary Concept]
- cycloSaligenyl-5-((E)-2-bromovinyl)-2'-deoxyuridine monophosphate [MeSH Supplementary Concept]
- thymectacin [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Broxuridine [ICD-11 Extension code]
- Broxuridine [NCIt concept]
- bromodeoxyuridine [Substance BNPC]

Keyword's position in hierarchy(ies) :

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