Preferred Label : bromelains;
MeSH definition : Protein-digesting and milk-clotting enzymes found in PINEAPPLE fruit juice and stem
tissue. Enzymes from the two sources are distinguished as fruit bromelain and stem
bromelain. This enzyme was formerly listed as EC 3.4.22.4.;
MeSH synonym : bromelins; Bromelain; bromelin;
CISMeF synonym : bromelaine; bromelain, juice; Rhône-Poulenc rorer brand 1 of bromelains; Rhône-Poulenc rorer brand 2 of bromelains; Rhône-Poulenc rorer brand 3 of bromelains; aventis brand of bromelains; bromelains aventis brand; bromelains mucos brand; bromelains nattermann brand; bromelains rottapharm brand; bromelains ursapharm brand; bromelains wiedemann brand; mucos brand of bromelains; nattermann brand of bromelains; rhône poulenc rorer brand 1 of bromelains; rhône poulenc rorer brand 2 of bromelains; rhône poulenc rorer brand 3 of bromelains; rottapharm brand of bromelains; teva pharmaceutical's brand of bromelain; ursapharm brand of bromelains; wiedemann brand of bromelains;
MeSH hyponym : dayto anase; proteozym; mucozym; extranase; traumanase; Bromelain-POS; dontisanin; ananase; debrase; Bromelain POS; BromelainPOS;
MeSH Related Number : EC 3.4.22.32 (stem bromelain); EC 3.4.22.33 (fruit bromelain);
Registry Number MeSH : 9001-00-7;
Wikipedia link : https://en.wikipedia.org/wiki/Traumanase;
Codes EINECS : 232-572-4;
Is substance : O;
Origin ID : D001963;
UMLS CUI : C0006217;
ATC code(s)
ATC code(s)
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Record concept(s)
Related MeSH Supplementary Concept(s)
- mekcase [MeSH Supplementary Concept]
- mexase [MeSH Supplementary Concept]
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
Protein-digesting and milk-clotting enzymes found in PINEAPPLE fruit juice and stem
tissue. Enzymes from the two sources are distinguished as fruit bromelain and stem
bromelain. This enzyme was formerly listed as EC 3.4.22.4.
http://www.has-sante.fr/portail/jcms/c_2561335/fr/nexobrid-concentre-d-enzymes-proteolytiques-riches-en-bromelaine-enzymes
http://www.has-sante.fr/portail/jcms/c_2561335/fr/nexobrid
2015
false
France
French
evaluation of the transparency committee
guidelines for drug use
insurance, health, reimbursement
bromelains
gels
debridement
peptide hydrolases
bromelains
treatment outcome
adult
orphan drug production
administration, cutaneous
pressure ulcer
burns
stem bromelain
stem bromelain
ananas
plant extracts
plant extracts
aged
continuity of patient care
Partial deep dermal and full thickness burns
bromelains
peptide hydrolases
---
https://www.ema.europa.eu/medicines/human/EPAR/NexoBrid
2013
false
United Kingdom
French
English
peptide hydrolases
bromelains
drug approval
treatment outcome
adult
orphan drug production
summary of product characteristics
package leaflet
drug evaluation
syndication feed
administration, cutaneous
pressure ulcer
burns
stem bromelain
stem bromelain
ananas
plant extracts
plant extracts
aged
continuity of patient care
drug interactions
pregnancy
breast feeding
debridement
drug evaluation, preclinical
bromelains
Partial deep dermal and full thickness burns
bromelains
peptide hydrolases
---
https://webprod.hc-sc.gc.ca/nhpid-bdipsn/monoReq.do?id=503&lang=fra
https://webprod.hc-sc.gc.ca/nhpid-bdipsn/monoReq.do?id=503&lang=eng
2011
Canada
French
English
drug information
canada
stem bromelain
bromelains
ananas
phytotherapy
plant stems
administration, oral
adult
plant preparations
drug labeling
---
https://webprod.hc-sc.gc.ca/nhpid-bdipsn/monoReq.do?id=502&lang=eng
https://webprod.hc-sc.gc.ca/nhpid-bdipsn/monoReq.do?id=502&lang=fra
2011
Canada
English
French
drug information
bromelains
fruit bromelain
canada
drug labeling
fruit
ananas
administration, oral
adult
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66242602
2008
France
French
tablets, enteric-coated
administration, oral
bromelains
drug information
---