Preferred Label : biotransformation;

MeSH definition : The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.;

CISMeF synonym : biotransformations; activations, metabolic; metabolic activations;

MeSH annotation : restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /pharmacokin (IM) or /metab; do not confuse with BIODEGRADATION, ENVIRONMENTAL;

Wikipedia link : https://en.wikipedia.org/wiki/Biotransformation;

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The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.

http://www.academie-medecine.fr/pharmacogenetique-et-pharmacogenomique-rapport-06-01/
2006
false
false
France
English
French
antivitamins K
anticoagulants
vitamin K
immunosuppressive agents
antineoplastic agents
mutation
pharmacogenetics
genomics
polymorphism, genetic
iatrogenic disease
Drug-Related side effects and adverse reactions
genotype
pharmaceutical preparations
biotransformation
iatrogenic disease
antivitamins K
guidelines
indenes
4-hydroxycoumarins

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29/07/2025


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