benserazide - CISMeF

Preferred Label : benserazide;

MeSH definition : An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.;

MeSH synonym : seryltrihydroxybenzylhydrazine; benzylhydrazine, seryltrihydroxy; dl-serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide; seryltrihydroxy benzylhydrazine; serazide;

MeSH hyponym : ro 4-4602; Ro 4 4602; Ro 44602;

MeSH CAS label : DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide;

MeSH Related Number : 322-35-0 (Benserazide);

Registry Number MeSH : 322-35-0;

Is substance : O;

UNII : 762OS3ZEJU;

InChIKey : BNQDCRGUHNALGH-UHFFFAOYSA-N;

Details

Origin ID

D001545;

UMLS CUI

C0005014;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Benserazide [ICHI extension code]
Manual BTNT mappings - CISMeF
- Benserazide hydrochloride (substance) [SNOMED CT concept]
Pharmacological action(s)
- antiparkinson agents [MeSH Descriptor]
- dopamine agents [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- benserazide [MeSH concept]
- ro 4-4602 [MeSH concept]
Related MeSH Supplementary Concept(s)
- benserazide, levodopa drug combination [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing benserazide (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- Benserazide hydrochloride [Substance BNPC]

Keyword's position in hierarchy(ies) :

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