3-pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, methyl ester

Preferred Label : 3-pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, methyl ester;

MeSH definition : A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2 influx through partially activated voltage-dependent Ca2 channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.;

MeSH hyponym : Bay K 8644; Bay R 5417; Bay-R-5417; Bay-K-8644, ( )-Isomer; Bay-K-8644; Bay-K-8644, ( -)-Isomer; Bay-K-8644, (-)-Isomer; BayR5417; Bay R5417; R5417, Bay; BayK8644; Bay-K8644; Bay K8644; BK-8644; BK 8644; BK8644;

MeSH CAS label : 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, methyl ester;

MeSH Related Number : Bay-K-8644, ( )-Isomer; Bay-K-8644, ( -)-Isomer; Bay-K-8644, (-)-Isomer; 97217-82-8 (( -)-isomer); 98625-26-4 ((-)-isomer); 98791-67-4 (( )-isomer);

Registry Number MeSH : 71145-03-4;

Related CAS MeSH : 97217-82-8 (Bay-K-8644, ( -)-Isomer); 98625-26-4 (Bay-K-8644, (-)-Isomer); 98791-67-4 (Bay-K-8644, ( )-Isomer);

MeSH annotation : a calcium channel agonist;

Is substance : O;

Details

Origin ID

D001498;

UMLS CUI

C1455839;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- calcium channel agonists [MeSH Descriptor]
Record concept(s)
- 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, methyl ester [MeSH concept]
- Bay-K-8644 [MeSH concept]
- Bay-K-8644, (+)-Isomer [MeSH concept]
- Bay-K-8644, (+-)-Isomer [MeSH concept]
- Bay-K-8644, (-)-Isomer [MeSH concept]
- Bay-R-5417 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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