arachidonate 12-lipoxygenase

Preferred Label : arachidonate 12-lipoxygenase;

MeSH definition : An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.;

MeSH synonym : 12-lipoxygenase; 12-lipoxygenase, arachidonic acid; 12 lipoxygenase; 12-lipoxygenase, arachidonate; arachidonic acid 12-lipoxygenase; arachidonic acid 12 lipoxygenase; arachidonate 12 lipoxygenase;

Wikipedia automatic translation : ALOX12;

MeSH CAS label : arachidonate:oxygen 12-oxidoreductase;

Registry Number MeSH : EC 1.13.11.31;

Wikipedia link : https://en.wikipedia.org/wiki/ALOX12;

Is substance : O;

UNII : EC 1.13.11.31;

Details

Origin ID

D001092;

UMLS CUI

C0003691;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ALOX12 Gene [NCIt concept]
- Arachidonate 12-Lipoxygenase, 12S-Type [NCIt concept]
- Arachidonate 12-lipoxygenase (substance) [SNOMED CT concept]
- Arachidonate 12-oxidoreductase [OMIM gene]
- arachidonate 12-lipoxygenase [SNOMED Notion]
- arachidonate 12-lipoxygenase, 12S type [HGNC gene]
Indexing information
- 4-(2-oxapentadeca-4-yne)phenylpropanoic acid [MeSH Supplementary Concept]
Record concept(s)
- arachidonate 12-Lipoxygenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- 12-15-lipoxygenase [MeSH Supplementary Concept]
- ALOX12 protein, human [MeSH Supplementary Concept]
- ALOX12B protein, human [MeSH Supplementary Concept]
- Alox12b protein, mouse [MeSH Supplementary Concept]
- Alox15 protein, mouse [MeSH Supplementary Concept]
- hepoxilin synthase [MeSH Supplementary Concept]
- lipoxin A4 synthase [MeSH Supplementary Concept]
- lipoxin B4 synthase [MeSH Supplementary Concept]
Related MeSH term(s)
- lipoxygenase inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Arachidonate 12-lipoxygenase (substance) [SNOMED CT concept]
- arachidonate 12-lipoxygenase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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