Preferred Label : apolipoproteins b;
MeSH definition : Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms,
apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100
expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS,
VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important
in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins.
Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.;
MeSH synonym : apo b; apob; apo-b;
MeSH Hyperonym : apoproteins B; Apoprotein (B);
Wikipedia link : https://en.wikipedia.org/wiki/Apob;
Is substance : O;
Origin ID : D001055;
UMLS CUI : C0003593;
Allowable qualifiers
- Currated CISMeF NLP mapping
- Indexing information
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms,
apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100
expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS,
VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important
in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins.
Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.
