anaphylatoxins

Preferred Label : anaphylatoxins;

MeSH definition : Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They induce smooth MUSCLE CONTRACTION; mast cell HISTAMINE RELEASE; PLATELET AGGREGATION; and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from the strongest to the weakest is C5a, C3a, C4a, and C5a des-arginine.;

MeSH synonym : Anaphylatoxin;

MeSH hyponym : anaphylatoxin;

Wikipedia link : https://en.wikipedia.org/wiki/Anaphylatoxins;

Is substance : O;

Details

Origin ID

D000706;

UMLS CUI

C0002791;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Anaphylatoxin (substance) [SNOMED CT concept]
- anaphylatoxin [SNOMED Notion]
Indexing information
- complement C3a, (70-77) [MeSH Supplementary Concept]
- complement C3a, des-Arg-(77)- [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- anaphylatoxins [MeSH concept]
See also inter- (CISMeF)
- Anaphylatoxin (disposition) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Hazardous or Poisonous Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Anaphylatoxin (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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