porphobilinogen synthase

Preferred Label : porphobilinogen synthase;

MeSH definition : An enzyme that catalyzes the formation of porphobilinogen from two molecules of 5-aminolevulinic acid. EC 4.2.1.24.;

MeSH synonym : acid dehydratase, delta-aminolevulinic; aminolevulinate hydro-lyase; aminolevulinic acid dehydratase; dehydratase, aminolevulinic acid; delta aminolevulinate dehydratase; delta aminolevulinic acid dehydratase; hydro-lyase, aminolevulinate; synthase, porphobilinogen; aminolevulinate hydro lyase; delta-aminolevulinate dehydratase; dehydratase, delta-aminolevulinate; delta-aminolevulinic acid dehydratase; dehydratase, delta-aminolevulinic acid; ala-dehydrase; ala dehydrase; acid dehydratase, aminolevulinic;

MeSH CAS label : 5-Aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing);

MeSH Related Number : 9036-37-7 (CAS RN);

Registry Number MeSH : EC 4.2.1.24;

MeSH annotation : DF: ALA DEHYDRASE;

Wikipedia link : https://en.wikipedia.org/wiki/Porphobilinogen synthase;

Is substance : O;

UNII : EC 4.2.1.24;

Details

Origin ID

D000623;

UMLS CUI

C0002564;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Porphobilinogen synthase [LOINC component]
- Porphobilinogen synthase (substance) [SNOMED CT concept]
- porphobilinogen synthase [SNOMED Notion]
Indexing information
- 2-amino-4-methoxy-3-butenoic acid [MeSH Supplementary Concept]
- 4,7-dioxosebacic acid [MeSH Supplementary Concept]
- 4-oxosebacic acid [MeSH Supplementary Concept]
- 5-chloro-4-oxopentanoic acid [MeSH Supplementary Concept]
- succinylacetone [MeSH Supplementary Concept]
Record concept(s)
- porphobilinogen synthase [MeSH concept]
Related MeSH Supplementary Concept(s)
- porphyria, acute hepatic [MeSH Supplementary Concept]
See also
- porphyrias [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Porphobilinogen synthase [LOINC component]
- Porphobilinogen synthase (substance) [SNOMED CT concept]
- porphobilinogen synthase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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