acetylcholinesterase

Preferred Label : acetylcholinesterase;

MeSH definition : An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.;

MeSH synonym : hydrolase, acetylcholine; acetylcholine hydrolase;

MeSH hyponym : acetylthiocholinesterase;

MeSH CAS label : acetylcholine acetylhydrolase;

Registry Number MeSH : EC 3.1.1.7;

MeSH annotation : reactivation or reactivators: coord NIM (with no qualif) with CHOLINESTERASE REACTIVATORS (IM); reactivation or reactivators: coordinate with CHOLINESTERASE REACTIVATORS;

Wikipedia link : https://en.wikipedia.org/wiki/Acetylcholinesterase;

Is substance : O;

UNII : EC 3.1.1.7;

Details

Origin ID

D000110;

UMLS CUI

C0001044;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- (9-amino-5,6,7,8-tetrahydroacridin-4-yl)methanol [MeSH Supplementary Concept]
- 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine [MeSH Supplementary Concept]
- 14-norhuperzine A [MeSH Supplementary Concept]
- 2-norbornyl-N-n-butylcarbamate [MeSH Supplementary Concept]
- 3-hydroxy-2-oxoindole [MeSH Supplementary Concept]
- 3-methyl-2-(4-methyl-1-piperazinyl)-N-(7-((1,2,3,4-tetrahydroacridin-9-yl)amino)heptyl)quinoline-4-carboxamide [MeSH Supplementary Concept]
- 6-(ethyl-(2-methoxybenzyl)amino)-1-(1'-(6-(ethyl-(2-methoxybenzyl)amino)hexanoyl)-(4,4')bipiperidinyl-1-yl)hexan-1-one [MeSH Supplementary Concept]
- 9-O-((2-(3-methyl)pyridinium)ethyl)berberine [MeSH Supplementary Concept]
- 9-O-(3-(naphthalene-2-ylthio)butyl)berberine [MeSH Supplementary Concept]
- AP 2238 [MeSH Supplementary Concept]
- N,N'-(3-methyl)phenylenediaminophosphorylchloridate [MeSH Supplementary Concept]
- O,O'-(3-methyl)phenylenediphorylchloride [MeSH Supplementary Concept]
- TZ2PA6 compound [MeSH Supplementary Concept]
- asporyergosterol [MeSH Supplementary Concept]
- bis(12)-hupyridone [MeSH Supplementary Concept]
- bis(18)-huperzine B [MeSH Supplementary Concept]
- ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo(b)(1,8)naphthyridine-3-carboxylate [MeSH Supplementary Concept]
- ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzo(1,8)naphthyridine-3-carboxylate [MeSH Supplementary Concept]
- heterophyllinine A [MeSH Supplementary Concept]
- heterophyllinine B [MeSH Supplementary Concept]
- ungiminorine [MeSH Supplementary Concept]
Record concept(s)
- acetylcholinesterase [MeSH concept]
- acetylthiocholinesterase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ACHE protein, human [MeSH Supplementary Concept]
- AchE peptide [MeSH Supplementary Concept]
- COLQ protein, human [MeSH Supplementary Concept]
- ColQ protein, rat [MeSH Supplementary Concept]
- PRX-105 [MeSH Supplementary Concept]
- ache protein, mouse [MeSH Supplementary Concept]
- ache protein, rat [MeSH Supplementary Concept]
- colq protein, mouse [MeSH Supplementary Concept]
- phosphonylated acetylcholinesterase [MeSH Supplementary Concept]
Related MeSH term(s)
- cholinesterase inhibitors [MeSH Descriptor]
See also (suggested by CISMeF)
- cholinesterase reactivators [MeSH Descriptor]
- rivastigmine [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Acetylcholinesterase [LOINC component]
- Acetylcholinesterase (substance) [SNOMED CT concept]
- acetylcholinesterase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients