MeSH definition : Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on
chromosome 6. They bind a restricted subset of peptides derived from the leader peptides
of other class I molecules. They primarily are involved with down-regulating cytolytic
activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.;
Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on
chromosome 6. They bind a restricted subset of peptides derived from the leader peptides
of other class I molecules. They primarily are involved with down-regulating cytolytic
activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.
Allowable qualifiers