Protein Glutamine gamma Glutamyltransferase 2

Preferred Label : Protein Glutamine gamma Glutamyltransferase 2;

MeSH definition : Calcium-dependent acyltransferase that catalyzes cross-linking of proteins at a GLUTAMINE in one chain with primary amine such as in LYSINE in another chain. In addition it can also accept monoamine substrates to catalyze post-translational modifications (e.g., protein serotonylation).;

MeSH synonym : Tissue-Type Transglutaminase; Tissue Type Transglutaminase; Transglutaminase, Tissue-Type; TGase II; Transglutaminase C; Transglutaminase II; TGM2 Proteins; Proteins, TGM2; Tissue Transglutaminase; Transglutaminase, Tissue; Transglutaminase 2;

MeSH annotation : distinguish from GAMMA-GLUTAMYLTRANSPEPTIDASE which is involved with glutathione metabolism;

UNII : EC 2.3.2.13;

Details

Origin ID

D000091345;

UMLS CUI

C5444761;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Protein-Glutamine Gamma-Glutamyltransferase 2 [NCIt concept]
- Tissue transglutaminase [LOINC component]
- Transglutaminase 2 [OMIM gene]
- transglutaminase 2 [HGNC gene]
Indexing information
- anti-transglutaminase autoantibody [MeSH Supplementary Concept]
Record concept(s)
- Protein Glutamine gamma Glutamyltransferase 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- TGM2 protein, human [MeSH Supplementary Concept]
- Tgm2 protein, mouse [MeSH Supplementary Concept]
- Tgm2 protein, rat [MeSH Supplementary Concept]
See also inter- (CISMeF)
- protein-glutamine gamma-glutamyltransferase activity [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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