Preferred Label : Mitochondrial Precursor Protein Import Complex Proteins;
MeSH definition : Multiprotein complexes that mediate import and sorting of mitochondrial preproteins
into one of the four mitochondrial subcompartments: the outer membrane, the intermembrane
space, the inner membrane, and the matrix. Mitochondrial protein import machinery
includes translocase of the outer membrane (TOM) complex, translocases of the inner
membrane (TIM) complex, beta‐barrel pathway complex, the mitochondrial intermembrane
space import and assembly (MIA) pathway complex, carrier proteins of the inner membrane
and the TIM23 complex and sorting and assembly machinery (SAM) complex.;
MeSH synonym : Mitochondrial Protein Import Machinery Proteins; Mitochondrial Precursor Protein Import Machinery Proteins;
MeSH hyponym : Preprotein Translocases, Mitochondrial; Translocases, Mitochondrial Preprotein; MIA Complex; SAM Complex; Import Complex, Mitochondrial; MIM Complex; TOMM Complex; TOMM Machinery; Translocase Outer Mitochondrial Membrane; TOM Translocase; Translocase, TOM; TOM Channel; Translocase of the Inner Membrane Complex; TIM Complex; TIMM Complex; Translocase of the Inner Mitochondrial Membrane Complex; TIM23 Complex;
Origin ID : D000090622;
UMLS CUI : C5544445;
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Automatic exact mappings (from CISMeF team)
Record concept(s)
Related MeSH Supplementary Concept(s)
Semantic type(s)
Multiprotein complexes that mediate import and sorting of mitochondrial preproteins
into one of the four mitochondrial subcompartments: the outer membrane, the intermembrane
space, the inner membrane, and the matrix. Mitochondrial protein import machinery
includes translocase of the outer membrane (TOM) complex, translocases of the inner
membrane (TIM) complex, beta‐barrel pathway complex, the mitochondrial intermembrane
space import and assembly (MIA) pathway complex, carrier proteins of the inner membrane
and the TIM23 complex and sorting and assembly machinery (SAM) complex.