Duocarmycins - CISMeF

Preferred Label : Duocarmycins;

MeSH definition : A group of pyrroloindole compounds often with additional spirocyclic unit(s) and their analogs originally isolated from STREPTOMYCES. They bind DNA minor grooves with adenine-N3 alkylation activity.;

MeSH synonym : Duocarmycin;

Wikipedia link : https://en.wikipedia.org/wiki/Duocarmycin;

Details

Origin ID

D000080890;

UMLS CUI

C1512091;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Duocarmycin Antineoplastic Antibiotic [NCIt concept]
Indexing information
- HNRNPL protein, human [MeSH Supplementary Concept]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
- antineoplastic agents, alkylating [MeSH Descriptor]
Record concept(s)
- Duocarmycins [MeSH concept]
Related MeSH Supplementary Concept(s)
- CC 1065 [MeSH Supplementary Concept]
- CC-1065-(N(3)-adenine)-DNA [MeSH Supplementary Concept]
- DU 86 [MeSH Supplementary Concept]
- KW 2189 [MeSH Supplementary Concept]
- N-acetyl-duocarmycin [MeSH Supplementary Concept]
- U 76073 [MeSH Supplementary Concept]
- U 76074 [MeSH Supplementary Concept]
- adozelesin [MeSH Supplementary Concept]
- bizelesin [MeSH Supplementary Concept]
- carzelesin [MeSH Supplementary Concept]
- duocarmycin A [MeSH Supplementary Concept]
- duocarmycin B1 [MeSH Supplementary Concept]
- duocarmycin B2 [MeSH Supplementary Concept]
- duocarmycin SA [MeSH Supplementary Concept]
- pyrindamycin A [MeSH Supplementary Concept]
- pyrindamycin B [MeSH Supplementary Concept]
- yatakemycin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
UMLS correspondences (same concept)
- Duocarmycin Antineoplastic Antibiotic [NCIt concept]

Keyword's position in hierarchy(ies) :

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