Alefacept - CISMeF

Preferred Label : Alefacept;

MeSH definition : A recombinant human fusion protein of LFA-3 antigen and immunoglobulin IGG1 that binds to CD2 ANTIGENS on memory T-LYMPHOCYTES, preventing their activation and proliferation. It is used in the management of moderate to severe chronic plaque PSORIASIS.;

MeSH synonym : LFA-3 IgG1 Fusion Protein; LFA 3 IgG1 Fusion Protein; LFA-3 IgG(1) Fusion Protein;

MeSH Related Number : 222535-22-0 (Alefacept);

UNII : ELK3V90G6C;

Details

Origin ID

D000077944;

UMLS CUI

C0962603;

ATC code(s)
- alefacept [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Alefacept [ICD-11 Extension code]
MeSH indexing information
- psoriasis [MeSH Descriptor]
Pharmacological action(s)
- dermatologic agents [MeSH Descriptor]
- immunologic factors [MeSH Descriptor]
Record concept(s)
- alefacept [MeSH concept]
- amevive [MeSH concept]
See also inter- (CISMeF)
- Product containing alefacept (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Alefacept [NCIt concept]
- Alefacept (substance) [SNOMED CT concept]
- Product containing alefacept (medicinal product) [SNOMED CT concept]
- alefacept [ATC Code]
Validated automatic mappings to BTNT
- alefacept [ATC Code]

Keyword's position in hierarchy(ies) :

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