Ivabradine - CISMeF

Preferred Label : Ivabradine;

MeSH definition : A benzazepine derivative and selective HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS inhibitor that lowers the heart rate. It is used in the treatment of CHRONIC STABLE ANGINA in patients unable to take BETA-ADRENERGIC BLOCKERS, and in the treatment of HEART FAILURE.;

MeSH hyponym : S-16257; S16257; S 16257 2; S 162572; S-16257-2; S162572; S-16260-2; S162602; S 16260-2; S 16260 2; S 162602;

MeSH CAS label : 2H-3-Benzazepin-2-one, 3-(3-((((7S)-3,4-dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-;

MeSH Related Number : 155974-00-8 (Ivabradine);

Wikipedia link : https://en.wikipedia.org/wiki/Ivabradine;

UNII : 3H48L0LPZQ;

Details

Origin ID

D000077550;

UMLS CUI

C0257190;

ATC code(s)
- carvedilol and ivabradine [ATC Code]
- ivabradine [ATC Code]
- metoprolol and ivabradine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Ivabradine hydrochloride (substance) [SNOMED CT concept]
MeSH indexing information
- cyclic nucleotide-gated cation channels [MeSH Descriptor]
- cyclic nucleotide-gated cation channels [MeSH Descriptor]
- stereoisomerism [MeSH Descriptor]
Pharmacological action(s)
- cardiovascular agents [MeSH Descriptor]
Record concept(s)
- 7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one [MeSH concept]
- Corlanor [MeSH concept]
- S 16257 [MeSH concept]
- S 16257-2 [MeSH concept]
- ivabradine [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- Ivabradine hydrochloride [Substance BNPC]
- Ivabradine hydrochloride (substance) [SNOMED CT concept]
- ivabradine [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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