Receptor, Transforming Growth Factor-beta Type II

Preferred Label : Receptor, Transforming Growth Factor-beta Type II;

MeSH definition : A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE I TGF-BETA RECEPTORS when bound to TGF-BETA. This receptor complex regulates a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.;

MeSH synonym : Receptor, Transforming Growth Factor beta Type II; TGF-beta Type II Receptor; TGF beta Type II Receptor; TGF-beta Type II Receptors; TGF beta Type II Receptors; Type II TGF-beta Receptors; Type II TGF beta Receptors; Transforming Growth Factor-beta Type II Receptor; Transforming Growth Factor beta Type II Receptor; Transforming Growth Factor-beta Type II Receptors; Transforming Growth Factor beta Type II Receptors; Type II TGF-beta Receptor; Type II TGF beta Receptor; TGFBR2; TbetaR-II Kinase; Kinase, TbetaR-II; TbetaR II Kinase;

Registry Number MeSH : EC 2.7.11.30;

UNII : EC 2.7.11.30;

Details

Origin ID

D000077294;

UMLS CUI

C0214897;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
MeSH indexing information
- transforming growth factor beta [MeSH Descriptor]
Record concept(s)
- Receptor, Transforming Growth Factor-beta Type II [MeSH concept]
Related MeSH Supplementary Concept(s)
- TGFBR2 protein, human [MeSH Supplementary Concept]
- Tgfbr2 protein, mouse [MeSH Supplementary Concept]
- Tgfbr2 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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