Regulatory-Associated Protein of mTOR

Preferred Label : Regulatory-Associated Protein of mTOR;

MeSH definition : An adaptor protein component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 that forms stoichiometric complexes with TOR KINASES, which it negatively regulates. It functions as a positive regulator of RIBOSOMAL PROTEIN S6 KINASES.;

MeSH synonym : Regulatory Associated Protein of mTOR; mTOR Regulatory-Associated Protein; RAPTOR Protein; RPTOR Protein;

Details

Origin ID

D000076223;

UMLS CUI

C3538725;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Regulatory associated protein of mtor [OMIM gene]
- Regulatory-Associated Protein of mTOR [NCIt concept]
- regulatory associated protein of MTOR complex 1 [HGNC gene]
Record concept(s)
- Regulatory-Associated Protein of mTOR [MeSH concept]
Related MeSH Supplementary Concept(s)
- RPTOR protein, human [MeSH Supplementary Concept]
- Rptor protein, mouse [MeSH Supplementary Concept]
- rptor protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Regulatory-Associated Protein of mTOR [NCIt concept]

Keyword's position in hierarchy(ies) :

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