MeSH definition : A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER.
It is expressed in different isoforms in various tissues and interacts with TUMOR
SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and
chromosomal rearrangements of the ING1 gene are associated with different cancers
including HEAD AND NECK NEOPLASMS.;
A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER.
It is expressed in different isoforms in various tissues and interacts with TUMOR
SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and
chromosomal rearrangements of the ING1 gene are associated with different cancers
including HEAD AND NECK NEOPLASMS.