Preferred Label : Angiopoietin-Like Protein 4;
MeSH definition : A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL
CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive
form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage.
ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN
SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis.;
MeSH synonym : ANGPTL4 Protein; Angiopoietin-related Protein 4; Angiopoietin related Protein 4; Angiopoietin like Protein 4; 4, Angiopoietin-Like Protein; Protein 4, Angiopoietin-Like;
CISMeF synonym : Angiopoietin-like 4 Protein; Angiopoietin like 4 Protein;
Origin ID : D000075803;
UMLS CUI : C4318429;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL
CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive
form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage.
ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN
SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis.
