MeSH definition : A Krupple-type transcription factor consisting of an N-terminal BTB DOMAIN and nine
CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression
and gene expression for tissue development and homeostasis; it may also function as
an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic
rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.; A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine
CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression
and gene expression for tissue development and homeostasis; it may also function as
an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic
rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.;
A Krupple-type transcription factor consisting of an N-terminal BTB DOMAIN and nine
CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression
and gene expression for tissue development and homeostasis; it may also function as
an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic
rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA. A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine
CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression
and gene expression for tissue development and homeostasis; it may also function as
an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic
rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.