MeSH definition : A multiprotein complex that functions as a peptide hydrolase, or isopeptidase to cleave
NEDD8 PROTEIN from the CULLIN and UBIQUITIN-PROTEIN LIGASES, controlling the activity
of the ligases. It is highly conserved in eukaryotes and typically consists of 8 subunits
(CSN 1-8 proteins). The COP9 signalosome was originally identified in plants, where
it controls gene transcription in response to light.;
A multiprotein complex that functions as a peptide hydrolase, or isopeptidase to cleave
NEDD8 PROTEIN from the CULLIN and UBIQUITIN-PROTEIN LIGASES, controlling the activity
of the ligases. It is highly conserved in eukaryotes and typically consists of 8 subunits
(CSN 1-8 proteins). The COP9 signalosome was originally identified in plants, where
it controls gene transcription in response to light.
Allowable qualifiers