MeSH definition : An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle,
and gastrointestinal muscles that functions in transepithelial anion transport and
smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS
OF CAJAL and plays a major role in chloride conduction by airway epithelial cells
and in tracheal cartilage development.;
MeSH synonym : Anoctamin 1; Transmembrane Protein 16A; TMEM16A Protein;
An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle,
and gastrointestinal muscles that functions in transepithelial anion transport and
smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS
OF CAJAL and plays a major role in chloride conduction by airway epithelial cells
and in tracheal cartilage development.