NADPH Oxidase 4

Preferred Label : NADPH Oxidase 4;

MeSH definition : An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.;

MeSH synonym : Oxidase 4, NADPH; Renal NAD(P)H Oxidase; Nox4 Protein; Renox NAD(P)H Oxidase;

Registry Number MeSH : EC 1.6.3.-;

Details

Origin ID

D000074663;

UMLS CUI

C3538759;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- NADPH Oxidase 4 [NCIt concept]
- NADPH oxidase 4 [HGNC gene]
- Nadph oxidase 4 [OMIM gene]
Record concept(s)
- NADPH Oxidase 4 [MeSH concept]
Related MeSH Supplementary Concept(s)
- NOX4 protein, human [MeSH Supplementary Concept]
- Nox4 protein, mouse [MeSH Supplementary Concept]
- Nox4 protein, rat [MeSH Supplementary Concept]
- Nox4 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NADPH Oxidase 4 [NCIt concept]

Keyword's position in hierarchy(ies) :

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