Solute Carrier Organic Anion Transporter Family Member 1B3

Preferred Label : Solute Carrier Organic Anion Transporter Family Member 1B3;

MeSH definition : A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.;

MeSH synonym : OATP8 Protein; Solute Carrier Family 21 Member 8 Protein; Liver-Specific Organic Anion Transporter-2; Liver Specific Organic Anion Transporter 2; OATP1B3 Protein; SLC21A8 Protein; SLCO1B3 Protein;

Details

Origin ID

D000074542;

UMLS CUI

C3813198;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- SLCO1B3 Gene [NCIt concept]
- SLCO1B3 Gene Positive [NCIt concept]
- SLCO1B3 wt Allele [NCIt concept]
- Solute Carrier Organic Anion Transporter Family Member 1B3 [NCIt concept]
- Solute carrier organic anion transporter family, member 1b3 [OMIM gene]
- solute carrier organic anion transporter family member 1B3 [ORDO Gene]
- solute carrier organic anion transporter family member 1B3 [HGNC gene]
Record concept(s)
- Solute Carrier Organic Anion Transporter Family Member 1B3 [MeSH concept]
Related MeSH Supplementary Concept(s)
- SLCO1B3 protein, human [MeSH Supplementary Concept]
- Slco1b2 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Solute Carrier Organic Anion Transporter Family Member 1B3 [NCIt concept]

Keyword's position in hierarchy(ies) :

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