Preferred Label : Receptors, Enterotoxin;
MeSH definition : Guanylate cyclase-coupled receptors that bind bacterial ENTEROTOXINS, as well as the
endogenous peptides guanylin and uroguanylin. Ligand binding stimulates production
of CYCLIC GMP by EPITHELIAL CELLS of the intestinal lumen, altering barrier permeability
and mucus secretion. Mutations in the gene (GUCY2C) encoding this receptor are associated
with some cases of hereditary diarrhea (Diarrhea 6) and MECONIUM ILEUS.;
MeSH synonym : Enterotoxin-Guanylin Receptors; Enterotoxin Guanylin Receptors; Receptors, Enterotoxin-Guanylin; Receptors, Guanyl Cyclase-C; Receptors, Guanyl Cyclase C; Guanyl Cyclase-C Receptors; Cyclase-C Receptors, Guanyl; Guanyl Cyclase C Receptors; Guanylin-Uroguanylin Receptors; Guanylin Uroguanylin Receptors; Receptors, Guanylin-Uroguanylin; Heat-Stable Enterotoxin Receptors; Enterotoxin Receptors, Heat-Stable; Heat Stable Enterotoxin Receptors; Receptors, Heat-Stable Enterotoxin; Enterotoxin Receptors; GC-C Receptors; GC C Receptors; Receptors, GC-C; Enterotoxin-Guanylin Receptor; Enterotoxin Guanylin Receptor; Receptor, Enterotoxin-Guanylin; Guanyl Cyclase-C Receptor; Guanyl Cyclase C Receptor; Receptor, Guanyl Cyclase-C; Receptor, Guanyl Cyclase C; Guanylyl Cyclase C; Cyclase C, Guanylyl; Heat-Stable Enterotoxin Receptor; Enterotoxin Receptor, Heat-Stable; Heat Stable Enterotoxin Receptor; Receptor, Heat-Stable Enterotoxin; Receptor, Enterotoxin; GC-C Receptor; GC C Receptor; Receptor, GC-C; Guanylin-Uroguanylin Receptor; Guanylin Uroguanylin Receptor; Receptor, Guanylin-Uroguanylin; Enterotoxin Receptor;
Registry Number MeSH : EC 4.6.1.2;
UNII : EC 4.6.1.2;
Origin ID : D000074261;
UMLS CUI : C0059392;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Related MeSH term(s)
- See also
- Semantic type(s)
Guanylate cyclase-coupled receptors that bind bacterial ENTEROTOXINS, as well as the
endogenous peptides guanylin and uroguanylin. Ligand binding stimulates production
of CYCLIC GMP by EPITHELIAL CELLS of the intestinal lumen, altering barrier permeability
and mucus secretion. Mutations in the gene (GUCY2C) encoding this receptor are associated
with some cases of hereditary diarrhea (Diarrhea 6) and MECONIUM ILEUS.
