Zinc Finger E-box Binding Homeobox 2

Preferred Label : Zinc Finger E-box Binding Homeobox 2;

MeSH definition : A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME.;

MeSH synonym : Zinc Finger E box Binding Homeobox 2; Zinc Finger E-box Binding Homeobox 2 Protein; Zinc Finger E box Binding Homeobox 2 Protein; Zeb2 Transcription Factor; Transcription Factor, Zeb2; Smad-Interacting Protein 1; Smad Interacting Protein 1;

Details

Origin ID

D000074165;

UMLS CUI

C4319768;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Zinc Finger E-Box-Binding Homeobox 2 [NCIt concept]
- Zinc finger e box-binding homeobox 2 [OMIM gene]
- zinc finger E-box binding homeobox 2 [ORDO Gene]
- zinc finger E-box binding homeobox 2 [HGNC gene]
Record concept(s)
- Zinc Finger E-box Binding Homeobox 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- ZEB2 protein, human [MeSH Supplementary Concept]
- ZEB2 protein, mouse [MeSH Supplementary Concept]
- Zeb2 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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